All brain diseases can be subdivided according to the level of destruction on lesions inside of brain tissue (Alzheimer's disease) and lesions on the level of blood flowing to the brain (stroke, vascular dementia).
The main reasons of the VBD is acute or chronic impairment of cerebral circulation that occurs in patients with:
- High blood pressure
- High blood sugar level
- Heart disease
- Violation of lipid composition of blood
Main types of VBD:
- Stroke – acute impairment of cerebral blood circulation that occurs as a consequence of lack of blood flow to the brain (ischemic stroke) or insolvency of the vascular wall, which leads to permeation of the blood to the brain substance (hemorrhagic stroke, cerebral infarction).
- Alzheimer's disease characterized by damage on the neuronal level.
- Vascular dementia – occurs because of chronic violations of cerebral blood circulation.
As a result of circulatory disorders occurs cells death in certain areas of the patients brain. The symptoms of VBD are very different and depend on the affected area.
Main manifestations symptoms of VBD are:
- Memory loss
- Decreased concentration
- Impaired speech
- Disorientation in the place and time
- Weakness and numbness in the extremities
The biggest effectiveness of the treatment VBD observed in the earlier stages of disease.
Existing therapies are limited due to weak regenerative ability of nervous tissue and the narrow "therapeutic window" - the time when therapy has best effect.
Usage of stem cells in the treatment of diseases of the brain expands "therapeutic window" and provides better effect of treatment.
The action of stem cells provides:
- Vasodilatation of existing and formation of new blood vessels in the brain;
- Recovery of nerve cells and myelin sheaths, conducting information;
After complex treatment of the patient using cell therapy in the majority of patients who applied in the early stages of the disease improves memory, sleep, normal speech, headaches, restores the ability to self-service. Efficiency of such kind of treatment is from 45 to 85%.